- March 12, 2014 - N30 Announces Start of Oral Dosing of N91115 in a Phase 1 Clinical Trial
- October 15, 2013 - N30 Announces Presentations at the 2013 North American Cystic Fibrosis Conference
- April 2, 2013 - N30 Announces Presentation of Preclinical Data at the Basic Science Meeting of the European Cystic Fibrosis Society
- March 13, 2013 - N30 Announces First Patient Treated in Clinical Trial of N6022 in Cystic Fibrosis
- October 8, 2012 - N30 Names Sherif Gabriel, Ph.D. as VP Research
- March 21, 2014 - Primary airway epithelial cells expanded with feeder cells and ROCK inhibitor for screening novel GSNOR inhibitors and CFTR correctorsPrimary airway epithelial cells expanded with feeder cells and ROCK inhibitor for screening novel GSNOR inhibitors and CFTR correctors
- March 21, 2014 - Identification of Novel, Efficacious F508del‐CFTR Correctors to Treat Cystic Fibrosis
- October 14, 2013 - Next generation F508del CFTR correctors using a YFP based high throughput screening assay
- October 14, 2013 - Intestinal Current Measurement to Assess Modulation of F508del-CFTR Function
- October 14, 2013 - A Novel GSNOR Inhibitor with Potent Bronchodilatory Effects and CFTR Potentiation Activity
More posters |
October 15, 2013 N30 Announces Presentations at the 2013 North American Cystic Fibrosis Conference
BOULDER, Colo., October 15, 2013 –N30 Pharmaceuticals, Inc. today announced presentations regarding its novel portfolio of compounds for the potential treatment of cystic fibrosis at the 2013 North American Cystic Fibrosis Conference, which will be held October 17-19, 2013 in Salt Lake City, Utah.
The presentations include preclinical data on its first-in-class inhibitors of S-nitrosoglutathione reductase (GSNORi) and its novel correctors of CFTR, the dysfunctional protein in cystic fibrosis. N30 Pharmaceuticals, Inc. is conducting a clinical trial of its lead compound, N6022 (an injectable formulation) in cystic fibrosis patients homozygous for the F508del mutation. More… PDF (34Kb)
See also two presentation posters in the Posters section of the N30Pharma website.
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- January 24, 2013 - Pharmacological Inhibition of S-Nitrosoglutathione Reductase Improves Endothelial Vasodilatory Function in Rats in vivo
- December 28, 2012 - ADH IB Expression, but Not ADH III, Is Decreased in Human Lung Cancer
- February 15, 2012 - Mechanism of Inhibition for N6022, a First-in-Class Drug Targeting GSNOR
- January 13, 2012 - Structure–activity relationship of pyrrole based GSNOR inhibitors
- August 25, 2011 - Preclinical 28-Day Inhalation Toxicity Assessment of S-Nitrosoglutathione
- July 26, 2011 - Discovery of potent and novel GSNOR inhibitors devoid of cytochrome P450 activities
- April 19, 2011 - Structure–activity relationships of pyrrole based GSNOR inhibitors: Pyrrole regioisomers and propionic acid replacement
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